Author/Authors :
Adedapo, A.A. University of Ibadan - Department of Veterinary Physiology, Biochemistry and Pharmacology, Nigeria , Ayodele, A.E University of Ibadan - Departments of Botany and Microbiology, Nigeria , Ogunshe, A. A. O. University of Ibadan - Department of Botany and Microbiology, Nigeria , Oyeyemi, M. O. University of Ibadan - Department of Veterinary Surgery and Reproduction, Nigeria , Idowu, S. O. University of Ibadan - Department of Pharmaceutical Chemistry, Nigeria , Ola-Davies, O.E. University of Ibadan - Department of Veterinary Physiology, Biochemistry and Pharmacology, Nigeria , Ademola, I. O University of Ibadan - Department of Veterinary Microbiology and Parasitology, Nigeria
Abstract :
A total of 20 domestic rabbits divided into 4 groups of 5 animals per group were used in this study to assess the haematinic potencies of the aqueous crude extracts of Ficus mucoso and Senna occidentalis and this was then compared with that of a proprietary haematinic, Haematopan B12®. Group A animals (control) were not bled but those in groups B, C and D were bled to induce anaemia. Group B animals were treated with Haematopan B12®, a commercially prepared haematinic, and groups C and D were treated with the aqueous crude extracts of Senna occidentalis (Linn) Link and Ficus mucoso Welw. ex Ficalho respectively. The post-haemorrhage treatment haematologic values were obtained at given intervals (7 days) and compared with the pre-haemorrhagic values earlier obtained. The study showed that all the experimental animals showed accelerated recovery since these animals had excellent response in terms of white blood cell (WBC) and its differentials, red blood cell (RBC) count, packed cell volume (PCV) and haemoglobin (Hb) concentration. Thus the extracts of Ficus mucoso and Senna occidentalis have comparative haematinic potencies as Haematopan B12®.
Keywords :
Haematopan B12® , anaemia , rabbits , Senna occidentalis , Ficus mucoso
