Title of article :
Antimicrobial Potency of Pentaclethra Macrophylla Seed Extract on Seven Selected Pathogens
Author/Authors :
Olaitan, J. O. University of Agriculture - College of Natural Sciences - Department of Microbiology, Nigeria , Olaitan, J. O. Osun State University - College of Science Engineering and Technology - Department of Biological Sciences, Nigeria , Kareem, S. O. University of Agriculture - College of Natural Sciences - Department of Microbiology, Nigeria , Dada, S. O. University of Agriculture - College of Natural Sciences - Department of Microbiology, Nigeria
Abstract :
The antimicrobial efficacy of extracts of Pentaclethra macrophylla in ethanol, methanol and water was determined against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella species, Salmonella typhi, Aspergills niger and Candida albican using paper disc and hole diffusion methods. The results revealed that the growths of test organisms were inhibited by extracts used. The least inhibitory zone (25.0mm) was best recorded in ethanol extract against A. niger and C. albicans. The minimum inhibitory concentration of the extracts ranges between 62.5-250mg/ml on the test isolates. However, the antimicrobial potency of Pentaclethra macrophylla was more prominent against bacterial isolates than fungal isolates. These findings lend more weight to the use of Pentaclethra macrophylla seed for therapeutic purposes.
Keywords :
Pentaclethra macrophylla , antibacterial , microorganism
Journal title :
African Journal of Biomedical Research
Journal title :
African Journal of Biomedical Research