Title of article :
Anti-inflammatory and Analgesic activities of Methanolic Extracts of the Stem Bark of Alstonia Boneei, Ficus Elastica and Xylopia Aethiopica in Rodents
Author/Authors :
Aziba, P. I Olabisi Onabanjo University - College of Health Sciences - Department of Pharmacology and Therapeutics, Nigeria , Sokan, J. A Olabisi Onabanjo University - College of Health Sciences - Department of Pharmacology and Therapeutics, Nigeria
Abstract :
The analgesic and anti-inflammatory properties of equimolar concentrations of the methanolic extracts of Alstonia Boneei (MEAB), Ficus Elastica (MEFE) and Xylopia Aethiopica (MEXA) were investigated in 0.1% acetic acid induced Pain (Writhing) in Mice , and 0.4ml of 0. 1% carrageenan induced inflammation in rats as a model of acute inflammation and compared with Indomethacin. The MEAB and MEXA at concentrations used did not produce significant or marked inflammatory and analgesic effects while MEFE significantly (p 0.05) inhibited carrageenan induced inflammation and acetic acid induced writhing.
Keywords :
Analgesic , inflammation , Alstonia Boneei , Ficus Elastica and Xylopia Aethiopica , extracts
Journal title :
African Journal of Biomedical Research
Journal title :
African Journal of Biomedical Research
