Author/Authors :
Okokon, Jude E. University of Uyo - Faculty of Pharmacy - Department of Pharmacology and Toxicology, Nigeria , Udoh, Anwanga E. University of Uyo - Faculty of Pharmacy - Department of Pharmacology and Toxicology, Nigeria , Frank, Samuel G. Akwa Ibom State Polytechnic - Department of Science Technology, Nigeria , Udo, Nsikak M. University of Uyo - Faculty of Pharmacy - Department of Pharmacology and Toxicology, Nigeria
Abstract :
Anti-inflammatory and antipyretic activities of leaf extract of Panicum maximum were evaluated to ascertain the folkloric claim of its use in fevers and inflammatory conditions. The crude leaf extract (48 – 144 mg/kg) of Panicum maximum was investigated for anti-inflammatory and antipyretic activities using various experimental models. The extract caused a significant (p 0.05 – 0.001) dose-dependent reduction in inflammation and fever induced by different agents used. The anti-inflammatory and antipyretic effects of this plant may in part be mediated through the secondary metabolites present in the plant.
Keywords :
Panicum maximum , Anti , inflammatory , antipyretic
