Title of article
A simple and efficient procedure for synthesis of optically active 1,3,4-oxadiazole derivatives containing L-amino acid moieties
Author/Authors
Foroughifar, Naser islamic azad university - Faculty of Chemistry, ايران , Foroughifar, Naser arak university - Department of Chemistry, اراك, ايران , Mobinikhaledi, Akbar arak university - Faculty of Science - Department of Chemistry, اراك, ايران , Ebrahimi, Sattar arak university - Department of Chemistry, اراك, ايران
From page
603
To page
611
Abstract
Some new unsymmetrical and optically active 2,5-disubstituted 1,3,4-oxadiazoles 5a-j were efficiently synthesized by cyclization reaction of diacylhydrazides 4a-j. The synthesis of the title compounds was achieved by the reaction of acyl hydrazides 3a-b and N-phetaloyl-L-amino acids 1a-e in the presence of the phosphoroxy chloride (POCl_3) as an anhydrous reagent.
Keywords
N , phetaloyl , L , amino acid , 1 , 3 , 4 , oxadiazole , diacylhydrazide , pyridoyl hydrazide , phosphoroxy chloride
Journal title
Turkish Journal of Chemistry
Journal title
Turkish Journal of Chemistry
Record number
2533022
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