Title of article
Chemical composition and antimicrobial activity of the essential oils of Geranium columbinum L. and G. lucidum L. (Geraniaceae)
Author/Authors
RADULOVIC, Niko University of Nis - Faculty of Science and Mathematics - Department of Chemistry, SERBIA , DEKIC, Milan University of Nis - Faculty of Science and Mathematics - Department of Chemistry, SERBIA , DEKIC, Milan University of Novi Pazar - Department of Biochemical and Medical Sciences State, SERBIA , STOJANOVIC RADIC, Zorica University of Nis - Faculty of Science and Mathematics - Department of Biology and Ecology, SERBIA , PALIC, Radosav University of Nis - Faculty of Science and Mathematics - Department of Chemistry, SERBIA
From page
499
To page
512
Abstract
The chemistry of Geranium columbinum and G. lucidum volatiles has been studied here for the first time. The essential oils were obtained by hydrodistillation, analyzed by GC and GC-MS, and screened for their in vitro antibacterial and antifungal activity in a microdilution assay. In total, 172 constituents were identified, accounting for 88.1%-96.7% of the detected GC peak areas. The essential oils consisted mainly of fatty acids and fatty acid-derived compounds (65.0%-86.3%). The major compounds of the essential oils were hexadecanoic acid, hexahydrofarnesyl acetone, and tetracosane. The antimicrobial assay showed a strong activity of the oil from aerial parts of G. columbinum against the pathogenic yeast C. albicans (MIC = 0.437, MBC = 1.75 mg/mL).
Keywords
Geranium columbinum , Geranium lucidum , Geraniaceae , essential oil composition , hexadecanoic acid , hexahydrofarnesyl acetone , tetracosane , antimicrobial activity
Journal title
Turkish Journal of Chemistry
Journal title
Turkish Journal of Chemistry
Record number
2533105
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