Title of article :
Simultaneous determination of dopamine, uric acid, and folic acid by a modified TiO_2 nanoparticles carbon paste electrode
Author/Authors :
Mazloum Ardakani, Mohammad yazd university - Faculty of Science - Department of Chemistry, يزد, ايران , SHEIKH MOHSENI, Mohammad Ali yazd university - Faculty of Science - Department of Chemistry, يزد, ايران , BEITOLLAHI, Hadi yazd university - Faculty of Science - Department of Chemistry, يزد, ايران , Benvidi, Ali yazd university - Faculty of Science - Department of Chemistry, يزد, ايران , Naeimi, Hossein university of kashan - Faculty of Chemistry - Department of Organic Chemistry, كاشان, ايران
Abstract :
The electrochemical behavior of dopamine (DA) was studied at the surface of a 2,2-[1,2 buthanediylbis(nitriloethylidyne)]- bis-hydroquinone/TiO2 nanoparticles modified carbon paste electrode (BQTMCPE) in aqueous media using voltammetric and chronoamperometric techniques. It was found that under optimum conditions (pH 8.0), the oxidation of DA at the surface of such an electrode occurred at about 220 mV lower than that of an unmodified carbon paste electrode (CPE). Using differential pulse voltammetry (DPV), a highly selective and simultaneous determination of DA, uric acid (UA), and folic acid (FA) was explored at the modified electrode. DPV peak currents of DA, UA, and FA increased linearly with their concentrations in the ranges of 1.0-900.0 μM, 200.0-1500.0 μM, and 200.0-2700.0 μM, respectively, and the detection limits for DA, UA, and FA were 0.3 μM, 12.0 μM, and 32.0 μM, respectively. This method was also used for the determination of DA in pharmaceutical preparation (DA injection) by the standard addition method.
Keywords :
Modified electrode , dopamine , uric acid , folic acid , TiO_2 nanoparticles
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry
