Title of article :
One-pot synthesis of fully substituted 1,3,4-oxadiazole derivatives from aromatic carboxylic acids, cyclobutanone and N-isocyaniminotriphenylphosphorane
Author/Authors :
VALIZADEH HOLAGH, Mohsen Baku State University - Chemistry Department, AZERBAIJAN , MAHARRAMOV, Abel Mohammadali oglu Baku State University - Chemistry Department, AZERBAIJAN , ALLAHVERDIYEV, Mirza Aliakbar oglu Baku State University - Chemistry Department, AZERBAIJAN , RAMAZANI, Ali zanjan university - Chemistry Department, زنجان, ايران , AHMADI, Yavar islamic azad university - Young Researchers Club, ايران , SOULDOZI, Ali islamic azad university - Chemistry Department, ايران
Abstract :
Reactions of N -isocyaniminotriphenylphosphorane with cyclobutanone in the presence of aromatic (or heteroaromatic) carboxylic acids proceeded smoothly at room temperature and in neutral conditions to afford sterically congested 1-(5-aryl-1,3,4-oxadiazol-2-yl)-1-cyclobutanol derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed. The structures of the products were deduced from their IR, ¹HNMR, and ¹³CNMR spectra, and mass spectrometry.
Keywords :
N , isocyaniminotriphenylphosphorane , intramolecular aza , Wittig reaction , 1 , 3 , 4 , oxadiazole , aromatic carboxylic acid , cyclobutanone
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry
