Author/Authors :
RAMAZANI, Ali zanjan university - Department of Chemistry, زنجان, ايران , DASTANRA, Kourosh zanjan university - Department of Chemistry, زنجان, ايران , ZEINALI NASRABADI, Fatemeh zanjan university - Department of Chemistry, زنجان, ايران , KARIMI, Zahra zanjan university - Department of Chemistry, زنجان, ايران , ROUHANI, Morteza islamic azad university - Young Researchers Club, ايران , HOSSEINI, Mehdi islamic azad university - Young Researchers Club, ايران
Abstract :
Reaction of an isocyanide with an iminium ion intermediate, formed by reaction between 2-oxo-2- phenylacetaldehyde and a secondary amine in the presence of silica nanoparticles, proceeds smoothly at room temperature to afford ketoamide derivatives in high yields.
Keywords :
Silica nanoparticles , multicomponent reaction , isocyanide , 2 , oxo , 2 , phenylacetaldehyde , secondary amine , iminium ion
