Title of article :
Three-component Passerini-Smiles coupling reaction of aldehydes and isocyanides with tropolone catalyzed by silica nanoparticles
Author/Authors :
MASSOUDI, Abdolhossain payame noor university - Department of Chemistry, تهران, ايران , AMINI, Issa payame noor university - Department of Chemistry, تهران, ايران , Ramazani, Ali islamic azad university - Department of Chemistry, ايران , ZEINALI NASRABADI, Fatemeh zanjan university - Department of Chemistry, زنجان, ايران
Abstract :
The use of Smiles rearrangement in Passerini-type couplings with tropolone allows very straightforward multicomponent formation of α-aryloxy amide derivatives. The 3-component addition of isocyanide to tropolone (2-hydroxy-2,4,6-cycloheptatrien-1-one) and aldehyde in the presence of silica nanoparticles (silica NP, ca. 70 nm) proceeds easily in methanol to form the title compounds in a new Passerini- Smiles-type reaction.
Keywords :
Smiles rearrangement , Passerini , type coupling , tropolone , isocyanide , silica nanoparticles , Passerini , Smiles , type reaction
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry
