Author/Authors :
SHEN, Tianhua Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , QIN, Quan Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , NI, Hang Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , XIA, Ting Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , ZHOU, Xiaocong Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , CUI, Funa Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , LI, Junqi Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , RAN, Deqiang Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China , SONG, Qingbao Zhejiang University of Technology - College of Chemical Engineering and Materials Science - The State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, China
Abstract :
The Cu(I)-based complex prepared from (S)-2-(furan-2-yl-methylamino)-2-phenylethanol (5c) and CuCl was used as catalyst in enantioselective Henry reactions of arylaldehydes and nitromethane, which gave 89% ee and 95% yield at ambient temperature. The proposed catalytic cycle of an asymmetric Henry reaction was suggested.
Keywords :
Chiral amino alcohol , copper(I) salt , asymmetric catalysis , Henry reaction
