Title of article :
N-functionalized benzimidazol-2-ylidene silver complexes: synthesis, characterization, and antimicrobial studies
Author/Authors :
GOK, Yetkin Inonu University - Faculty Science and Arts - Chemistry Department, TURKEY , AKKOC, Senem Erciyes University - Faculty of Science - Department of Chemistry, Turkey , OZEROGLU CELIKAL, Ozlem Inonu University - Faculty of Science and Arts - Department of Chemistry, Turkey , OZDEMIR, Ilknur Inonu University - Faculty of Arts and Sciences - Department of Chemistry, Turkey , GUNAL, Selami Inonu University - Faculty of Medicine - Department of Microbiology, Turkey , SAYIN, Elif Inonu University - Faculty of Science and Arts - Department of Chemistry, Turkey
Abstract :
2-Methoxyethyl, 2-diethylaminoethyl, and 2-phenylethyl-substituted N-heterocyclic carbene (NHC) precursors were treated with Ag_2CO_3 to yield silver(I)-NHC complexes (1a--g) in dichloromethane as a solvent at room temperature. The 7 new silver-NHC complexes were fully characterized by means of ^1H NMR, ^{13}C NMR, and elemental analysis techniques. Using the agar dilution procedure recommended by the Laboratory and Clinical Standards Institute, the antimicrobial activities of all the silver-NHC complexes were studied against 2 gram-negative bacterial strains (Pseudomonas aeruginosa and Escherichia coli), 2 gram-positive bacterial strains (Enterococcus faecalis and Staphylococcus aureus), and 2 fungi (Candida tropicalis and Candida albicans).
Keywords :
N , Heterocyclic carbene , benzimidazol , 2 , ylidene , silver complex , antimicrobial activity , medical inorganic chemistry
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry
