Title of article
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
Author/Authors
MOHAMED GOMHA, Sobhi University of Cairo - Faculty of Science - Department of Chemistry, Egypt , SAMI SHAWALI, Ahmad University of Cairo - Faculty of Science - Department of Chemistry, Egypt , OSMAN ABDELHAMID, Abdou University of Cairo - Faculty of Science - Department of Chemistry, Egypt
From page
865
To page
879
Abstract
A new, less expensive, solvent-free procedure was developed for the synthesis of some new derivatives of various fused heterocyclic ring systems, namely azolopyridazine, azolotriazine, azinotriazine, thienopyridine, and pyrazolopyridine. The structures of the products prepared were established by their spectral data and elemental analyses. Eight compounds were evaluated for their in vitro antimicrobial activity. Some of the tested compounds exhibited moderate to significant antibacterial and antifungal activities.
Keywords
Azolopyridazine , azolotriazine , azinotriazine , thienopyridine , pyrazolopyridine , antimicrobial activities
Journal title
Turkish Journal of Chemistry
Journal title
Turkish Journal of Chemistry
Record number
2533400
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