Title of article :
Bioassay studies of 2 -O-ethylmurrangatin isolated from a medicinal plant, Murraya paniculata
Author/Authors :
SHAIKH, Azizuddin Federal Urdu University of Arts, Science Technology, Gulshan-e-Iqbal Campus - Department of Chemistry, PAKISTAN , CHOUDHARY, Muhammad Iqbal University of Karachi - International Center for Chemical and Biological Sciences, H E J Research Institute of Chemistry, PAKISTAN
Abstract :
A secondary metabolite, 2 -O-ethylmurrangatin (1), was isolated from the leaves of a medicinal plant, Murraya paniculata. The structure of compound 1 was identified with the help of spectroscopic techniques. Compound 1 was screened for its antioxidant, lipoxygenase, prolyl endopeptidase, and respiratory burst inhibitory activities. 2 -O-Ethylmurrangatin (1) was found to have significant activity against lipoxygenase enzyme and moderate respiratory burst inhibitory activity, but no activity against either DPPH radical scavenging assay or prolyl endopeptidase enzyme.
Keywords :
Murraya paniculata , Rutaceae , 2 , O , ethylmurrangatin , antioxidant , DPPH radical scavenging assay , lipoxygenase inhibition assay , prolyl endopeptidase inhibition assay , respiratory burst inhibitory assay
Journal title :
Turkish Journal of Biology
Journal title :
Turkish Journal of Biology
