Droplet Counter Current Chromatography (DCCC) in herbal analysis

About half a century ago, the separation science was blessed with the introduction of a new liquid-liquid separation technique called droplet counter current chromatography (DCCC) that combined principles of counter current distribution and counter current chromatography, and employed a liquid stationary phase held in a cluster of vertical glass columns connected in series. In fact, DCCC is based on the partitioning of solutes between a constant stream of droplets of mobile phase and a column of surrounding stationary phase.