Title of article :
Efficacy of artemether-lumfantrine (Co-Artesiane^®) suspension in the treatment of uncomplicated Plasmodium falciparum malaria among children under 5 years in eastern Sudan
Author/Authors :
Salah, Muntaisr T. Ribat University, Sudan , Faroug, Mohamed Kassala University, Sudan , Magzoub, Mamoum M. Kassala University, Sudan , Adam, Ishag University of Khartoum - Faculty of Medicine, Sudan , Adam, Ishag Academy of Medical Sciences and Technology, Sudan
Abstract :
Purpose the aim of the present study was to investigate the efficacy of artemether-lumfantrine (Co-Artesiane^®) suspension for the treatment of uncomplicated Plasmodium falciparum malaria in children (aged 6-59 months) in Kassala in eastern Sudan. Method This was a prospective clinical trial where the artemether-lumfantrine (Co-Artesiane^®) suspension was given for three days and the patients were followed-up for 28 days Results: Forty-eight patients were enrolled in the study and 43 of them completed the 28-days follow-up. Treatment rapidly cleared parasitemia and fever. The overall 28-day cure rate was 100% and no clinical or parasitological failures were observed among these patients. Mild side effects were observed in three (7%) children. Conclusion: Artemether-lumfantrine (coartem) suspension appears to be efficacious and safe for the treatment of uncomplicated malaria.
Keywords :
Artemether , lumfantrine , Co , Artesiane , children , falciparum , malaria , Sudan
Journal title :
Tropical Journal of Pharmaceutical Research
Journal title :
Tropical Journal of Pharmaceutical Research
