Fibrin Sealant in the Management of Fistula in-Ano

The present study was carried out to assess the efficacy and advantages of fibrin therapy in anal fistulae. 50 patients with anal fistulae were treated by autologous fibrin glue prepared from platelets extract. Preoperative mechanical as well as chemical bowel preparation were adopted. The results were extremely satisfactory in the cured 35 patients (70%), whereas the remaining 15 patients (30%) showed recurrence. The significant causes of recurrence were long duration of the disease, previous surgery, and high fistulous tracts. The mean operative time was 18 minutes, and the mean hospital stay was 1.5 days with marked reduction in the use of postoperative analgesics. The anal continence was not affected in any of the patients (0% incontinence).