Author/Authors :
YASSIN, HAZEM M. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt , EL-HELW, MOSTAFA A. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt , EMARAH, AHMAD M. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt , ABOU HUSSEIN, NAHLA B. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt , HABIB, AHMAD E. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt , FOUSHAN, FATHY F. Cairo University - Faculty of Medicine - Department of Ophthalmology, Egypt
Abstract :
Purpose: To evaluate the role of riboflavin and ultraviolet- A (UVA) corneal collagen crosslinking in preventing the progression of keratectasia after laser in situ keratomileusis.Patients and Methods: Corneal crosslinking was performed in 1 eye of 13 patients that had laser in situ keratomileusis (LASIK) for myopia and myopic astigmatism and subsequently developed iatrogenic keratectasia.Results: Corneal collagen crosslinking induced by riboflavin and UVA was able to arrest and/or partially reverse keratectasia over a postoperative follow-up of up to 24 months as demonstrated by preoperative and post-operative corneal topography, keratometric readings and ultrasonic pachymetry.Conclusion: Riboflavin-UVA corneal crosslinking in¬creased the biomechanical stability of the cornea and may thus be a therapeutic means to arrest and partially reverse the progression of LASIK-induced iatrogenic keratectasia.
Keywords :
Collagen crosslinking , Post LASIK ectasia , Riboflavin , Ultraviolet , A
