Author/Authors :
Aboul-Fotouh, Sawsan Ain Shams University - Faculty of Medicine - Department of Pharmacology, Clinical Pharmacology Unit, Egypt , Abdallah, Nihad Ain Shams University - Faculty of Medicine - Department of Anesthesia and Intensive Care, Egypt , Saleh, Lobna A. Ain Shams University - Faculty of Medicine - Department of Pharmacology, Clinical Pharmacology Unit, Egypt , El-Shaer, Ahmed Ain Shams University - Faculty of Medicine - Department of Anesthesia and Intensive Care, Egypt , Abdel-Tawab, Ahmed M. Ain Shams University - Faculty of Medicine - Department of Pharmacology, Clinical Pharmacology Unit, Egypt
Abstract :
Vancomycin is widely used against methicillin-resistant Staphylococcus aureus (MRSA) infections. However, it is associated with two types of hypersensitivity reactions – an anaphylactoid reaction known as the ‘red man syndrome’ and anaphylaxis. Vancomycin-induced hypersensitivity occurs much more often at a younger age and is rarely seen in the elderly. Here, we report the case of a 78-year-old woman, who developed a hypersensitivity reaction following vancomycin infusion, which was administered for the treatment of MRSA pneumonia. Vancomycin was stopped and replaced by teicoplanin. The prevention and management of vancomycininduced hypersensitivity are also discussed.
