Glycosylated Haemoglubin Level and Severity of Coronary Artery Disease

Diabetes mellitus (DM) is known to cause microvascular and possibly macrovascular complications. This study was designed to evaluate the association between glycosylated hemoglobin (HbA1c) level and the severity of coronary artery disease. 100 diabetic Patients scheduled for cardiac catheterizations were enrolled in this study. The severity of CAD was assessed using the Gensini score. Hypertension was present in 66 patients, dyslipidemia in 43 patients, obesity in 35 patients, and family history of IHD was present in 29 patients, 39 patients were smokers. The mean Gensini score was 55±14 and the mean HbA1c was 11.3±4.2%. There was a significant positive correlation between Gensini score and HbA1c, also between Gensini score and both duration of DM and age. We can conclude that there was a positive correlation between glycosylated hemoglobin of patients, severity of CAD, age and duration of diabetes.