Evaluation of Ovarian Reserve in Infertile Women with Minimal/Mild Endometriosis

Aim: To evaluate the ovarian reserve in infertile women with minimal to mild degrees of endometriosis in comparison to infertile women with tubal factor. Methods: In a case-control study was run at Ain Shams University Maternity Hospital, 40 infertile patients, undergoing laparoscopy were divided into 2 groups Group A: Patients with minimal or mild endometriosis (Stage I or II) (n=20). Group B: Patients with tubal factor without endometriosis (n=20). The outcome Measures were serum FSH, E2, antiMullerian hormone (AMH), and the antral follicular count (AFC). Results: The number of antral follicles, follicles 8mm in diameter and the AMH level were significantly lower in endometriosis group in comparison to the control group. There was no statistically difference regarding E2 or FSH. Conclusions: The ovarian reserve is decreased in minimal to mild endometriosis which is demonstrated by measuring AMH and AFC. This finding needs further investigation.