TIMI Risk Score as A Predictor for No-Reflow Phenomenon in Patients Undergoing Primary Angioplasty for Acute STEMI

Background: Angiographic no-reflow phenomenon after primary Percutaneous Coronary Intervention (PCI) in patients with acute ST-elevation myocardial infarction (STEMI) may result in unfavorable outcome. Objectives: The aim of the study was to evaluate the TIMI risk score of STEMI as a predictor of no-reflow phenomenon after primary PCI. Patients and Methods: We analyzed 627 patients present-ing with acute STEMI and underwent primary PCI within 24 hours of symptoms onset, we divided the patients into high risk patients (TIMI risk score !5) and low risk patients (TIMI risk score 0-4). Results: The rate of no-reflow phenomenon was signifi-cantly higher in the high risk group compared to the low risk group (22% vs. 6.9% p:0.001), the c-statistics predictive value of the TIMI score for no reflow was 0.78 (p.001). After application of multivariate regression analysis, TIMI risk score of STEMI was an independent predictors of no-reflow phenomenon odds ratio 1.71 (CI 95% 1.31-2.1). Conclusion: TIMI risk score of STEMI on admission can predict angiographic no-reflow phenomenon after primary PCI.