Systematic Review: Effect of Compression Therapy on Lymphedema

Background: Breast Cancer Related Lymphedema (BCRL) is the most common chronic impairment following breast cancer surgery and or radiotherapy. The incidence of (BCRL) varies from 0 to 34%. Aim of the Study: The aim of this work was to systematically review the studies which assess of Effect of compression Therapy on lymphedema. Material and Methods: Systematic review of all published studies with all research designs except expert opinions. A search was made in pub med, Cochrane library, PEDro and Google scholar. Results: 6 studies met the inclusion criteria. Meta-analysis could be done and findings are presented qualitatively due to heterogeneity of the studies. There is conflicting evidence on whether compression therapy can decrease the lymphedema volume (circumference). Three studies under goes meta-analysis for the outcome of lymphedema reduction assessed by volumetric measurement and limb circumference differences on other two studies and one study under goes descriptive analysis. Conclusion: The current level of evidence to support the effectiveness of compression therapy on lymphedema post-mastectomy which was included in meta-analysis remains weak.