Comparative Study of Predictive Value of 2D Ultrasonography, Doppler of the Endometrium before and after HCG Injection on the Outcome of IVF/ICSI Cycles

Objective: Is to compare the value of measuring endometrial thickness and sub-endometrial blood flows by 2D ultrasound and Doppler to predict pregnancy during IVF/ ICSI treatment.Study Design: 50 women candidate for IVF. Two D ultrasound and color, Doppler of blood flow and endometrial thickness were studied on the day of HCG administration in the sub-endometrial zone and remeasured at day of embryo transfer. Patients were divided into two groups: Group A included 21 women with successful outcome (pregnancy) and Group B included 29 women with failure of pregnancy.Results: There was no significant difference between endometrial thickness measured before and after HCG trigerring and between pregnant and non pregnant women (p 0.5). The mean RI in patients before HCG injection was higher than that after HCG injection, the difference is statistically significant (p-value 0.025). The mean RI in no pregnancy group is higher than in pregnancy group, the difference, is statistically significant (p-value 0.01). The mean PI in patients before HCG injection was higher than that after HCG injection the difference is statistically significant (p-value 0.034).The mean PI in no pregnancy group is higher than in pregnancy group, the difference is statistically significant (p-value 0.02). The mean S/D ratio is higher in patients before HCG injection than that after HCG injection, the difference is statistically significant (p-value 0.041).The mean S/D ratio is lower in pregnancy group, the difference is statistically significant (p-value 0.04).Conclusion: Assessment of sub-endometrial blood flow by 2D colour Doppler ultrasound performed before and after HCG injection in patients undergoing IVF/ICSI cycle is a good predictor of pregnancy rate.