Author/Authors :
Lawson, L. Zankli Medical Centre, Nigeria , Habib, A. G. Aminu Kano Teaching Hospital - Department of Medicine, Nigeria , Habib, A. G. Institute of Human Virology Nigeria (IHVN), Nigeria , Okobi, M. I. Wuse General Hospital, Nigeria , Idiong, D. Zankli Medical Centre, Nigeria , Olajide, I. Zankli Medical Centre, Nigeria , Emenyonu, N. Zankli Medical Centre, Nigeria , Onuoha, N. Zankli Medical Centre, Nigeria , Cuevas, L. E. Liverpool School of Tropical Medicine, UK , Ogiri, S. O. Liaison Office, PMB 208 - World Health Organization (WHO), Nigeria
Abstract :
Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.
Keywords :
Drug resistance , human immunodeficiency virus , prevalence , Nigeria , tuberculosis
