Title of article :
Solvent-free One Pot Biginelli Method for Synthesis of new Dihydropyrimidinone compounds
Author/Authors :
Golkari, Masih Department of polymer engeeniering - Islamic Azad UniversityTehra Science and Reaserch Branch,Tehran, Iran
Abstract :
An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.
Keywords :
Biginelli reaction , Dihydropyrimidinones , One-pot , Solvent-free
Journal title :
International Journal of Heterocyclic Chemistry
