Title of article
Solvent Free Synthesis of tetra alkyl- phenyl-1H-pyrimido [4, 5-e][1,3,4]Thiadiazine-3,7-diamines
Author/Authors
Mohammadi, Mohammad Kazem Department of chemistry - Islamic Azad University Ahvaz Branch, Ahvaz, Iran
Pages
11
From page
67
To page
77
Abstract
New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines in simple and efficient methods.
Keywords
heterocyclization , 5- bromo- 2,4- dichloro-6- methylpyrimidine , 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine , phenylthioisothiocyanate
Journal title
International Journal of Heterocyclic Chemistry
Serial Year
2019
Record number
2544317
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