Author/Authors :
Aoyama، Yasutaka نويسنده , , Yamane، Takahisa نويسنده , , Hino، Masayuki نويسنده , , Nakamae، Hirohisa نويسنده , , Koh، Ki-Ryang نويسنده , , Takubo، Takayuki نويسنده , , Tatsumi، Noriyuki نويسنده , , Kumura، Takeo نويسنده , , Nishiki، Saori نويسنده , , Kinoshita، Yoshimitsu نويسنده , , Ohta، Kensuke نويسنده , , Kamitani، Tomio نويسنده , , Nakao، Takafumi نويسنده ,
Abstract :
Littoral cell angioma (LCA) is a rare vascular tumor of the spleen with an unknown etiology and unclear natural history. An association with synchronous malignancy has been described. We report the case of a 54-year-old woman who had progressive splenomegaly over 3 years following resection of a colon adenocarcinoma. The splenomegaly was associated with portal hypertension and severe thrombocytopenia. Splenectomy was performed, and the histologic and immunocytochemical features of the spleen specimen were consistent with LCA. The relationship between LCA and malignancy is reviewed.
