Author/Authors :
habibi, Laleh tehran university of medical sciences tums, تهران, ايران , perry, George the university of texas at san antonio - department of biology, United States , mahmoudi, Morteza Stanford University School of Medicine - Division of Pediatric Cardiology - Department of Pediatrics, USA , mahmoudi, Morteza tehran university of medical sciences tums - Nanotechnology Research Center, School of Pharmacy - Department of Nanotechnology, تهران, ايران
Abstract :
Climate change is having considerable impact on biological systems. Eras of ice ages and warming shaped the contemporary earth and origin of creatures including humans. Warming forces stress conditions on cells. Therefore, cells evolved elaborate defense mechanisms, such as creation of heat shock proteins, to combat heat stress. Global warming is becoming a crisis and this process would yield an undefined increasing rate of neurodegenerative disorders in future decades. Since heat stress is known to have a degenerative effects on neurons and, conversely, cold conditions have protective effect on these cells, we hypothesize that persistent heat stress forced by global warming might play a crucial role in increasing neurodegenerative disorders.
