Title of article :
Difficulties in Diagnosis of Hemophagocytic Lymphohistocytosis: Overdiagnosis or Underdiagnosis; A Case Report
Author/Authors :
Hashemieh, Mozhgan shahid beheshti university of medical sciences - Imam Hossein Medical center, تهران, ايران , Taslimi Taleghani, Naeeme shahid beheshti university of medical sciences - Imam Hossein Medical center, تهران, ايران , Sheibani, Kourosh shahid beheshti university of medical sciences - Clinical Research and Devalopment Center, Imam Hossein Medical center, تهران, ايران
Abstract :
Hemophagocytic lymphohistocytosis (HLH) is a potentially life threatening condition occurring as a familial disease (FHLH) or secondary to marked immunological activation during viral, bacterial and parasitic infections, malignancies, rheumatologic conditions or immune deficiencies with cytotoxic T and/or NK-cell dysfunction 1, 2. Although FHLH is an autosomal recessive disease that affects immune regulation, sporadic cases with no obvious family inheritance occur1. All organ systems might be affected in HLH.
Keywords :
Hemophagocytic Lymphohistocytosis , Multiple organ dysfunction syndromes , Sepsis , Systemic inflammatory response syndrome
Journal title :
Iranian Journal of Blood and Cancer (IJBC)
Journal title :
Iranian Journal of Blood and Cancer (IJBC)
