Myelofibrosis due to Secondary Hyperparathyroidism in a Case of Celiac Disease

Celiac sprue is an autoimmune disease caused by gluten-containing diet in genetically predisposed persons. Pathogenesis is presence of antibodies to tissue transglutaminase, endomyosium, reticulin, and gliadin.1 It leads to malabsorption of nutrients in small intestine such as iron, folate, and calcium.2 Presentations of patients with celiac disease are different including chronic diarrhea, short statue, iron deficiency anemia, osteomalacia, neurologic problems, and other unusual manifestations. Associatedconditions include dermatitis herpetiformis, selective IgA deficiency, and other diseases which have autoimmune bases such as type 1 diabetes mellitus, thyroid disease, and liver disease.1