Author/Authors :
Eshghi, Peyman shahid beheshti university of medical sciences - Department of Pediatric Hematology/Oncology, تهران, ايران , Goudarzipour, Kourosh shahid beheshti university of medical sciences - Department of Pediatric Hematology/Oncology, تهران, ايران , Davoudabadi, F. Hoorieh Centeral Hospital of National Iranian Oil Company, ايران , Aghakhani, Roxana shahid beheshti university of medical sciences - Department of Pathology, تهران, ايران
Abstract :
Background:Chronic synovitis is one of the most important complications in haemophilic patients. Rifampin is an antibiotic which its intra-articular injection leads to destruction of the synovial membrane of haemophilic patients medically. Materials and Methods: Between September 2003 and November 2005, we administered intra-articular rifampin in ١6 haemophilic joints of ٨ haemophilic patients. Results:Median age of our patients was 14.5 year-old. There were 11 knee joints and 5 elbow joints. Atier treatment we observed significant improvement in treated joints. Conclusion:This study reveals that intra-articular injection of rifampin may improve arthropathy in haemophilic patients.