Title of article :
CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF THE ESSENTIAL OIL OF FERULAGO BERNARDII TOMK. AND M. PIMEN.
Author/Authors :
KHALIGHI-SIGAROODI, FARAHNAZ tehran university of medical sciences tums - Department of Pharmacognosy, تهران, ايران , HADJIAKHOONDI, ABBAS tehran university of medical sciences tums - Department of Pharmacognosy, تهران, ايران , HADJIAKHOONDI, ABBAS tehran university of medical sciences tums - Herbal Medicine Research Center, تهران, ايران , SHAHVERDI, AHMADREZA tehran university of medical sciences tums - Faculty of Pharmacy - Department of Pharmaceutical Biotechnology, تهران, ايران , MOZAFFARIAN, VALI-ALLAH tehran university of medical sciences tums - Research Institute of Forests and Rangelands, تهران, ايران , SHAFIEE, ABBAS tehran university of medical sciences tums - Faculty ofPharmacy - Department of Chemistry and Pharmaceutical Sciences Research Center, تهران, ايران
Abstract :
The chemical composition of the essential oil of the aerial parts of Ferulago Bernardii from Iran wasanalysed by GC and GC/MS. Sixty constituents were found representing 87.9% of the oil. The mainconstituents of the essential oil were 2,4,5-trimethyl-benzaldehyde (21.2%), α-pinene (17.0%),spathulenol (5.0%), cis-chrysanthenyl acetate (4.4%) and caryophyllene oxide (3.2%). Antimicrobialactivity of the essential oil of Ferulago Bernardii by the broth dilution method in comparison withGentamycin and Fluconazole as standard showed weak activity against Staphylococcus aureus, Bacilussubtilis, Escherichia coli, Candida albicans and Aspergillus niger. The essential oil did not show anyactivity against Pseudomonas aeruginosa.
Keywords :
Ferulago Bernardii , Apiaceae , Essential oil composition , 2 , 4 , 5 , trimethyl , benzaldehyde , α , pinene , Antimicrobial activity
Journal title :
Daru:Journal of Pharmaceutical Sciences
Journal title :
Daru:Journal of Pharmaceutical Sciences
