Title of article :
PHYTOCHEMICAL STUDY OF PHLOMIS OLIVIERI BENTH. AND PHLOMIS PERSICA BOISS.
Author/Authors :
SARKHAIL, PARISA tehran university of medical sciences tums - Pharmaceutical Sciences Research Center, تهران, ايران , MONSEF- ESFEHANI, HAMID REZA tehran university of medical sciences tums - Faculty of Pharmacy - Department of Pharmacognosy, تهران, ايران , AMIN, GHOLAMREZA tehran university of medical sciences tums - Faculty of Pharmacy and Pharmaceutical Sciences Research - Department of Pharmacognosy, تهران, ايران , SALEHI SURMAGHI, MOHAMMAD HOSSEIN tehran university of medical sciences tums - Faculty of Pharmacy - Department of Pharmacognosy, تهران, ايران , SHAFIEE, ABASS tehran university of medical sciences tums - Faculty of Pharmacy - Department of Medicinal Chemistry and Pharmaceutical Sciences Research Center, تهران, ايران
Abstract :
Ethyl acetate and n- butanol fractions obtained from the column chromatography of methanolic extract of aerial parts of P. olivieri gave chrysoeriol-7-O-β-D-glucoside (I) and verbascoside (II), respectively. In addition, two flavonoid glycosides as compound (I) and chrysoeriol-7-β-D- (3 -E-p-coumaroyl) glucoside (III) and one iridoid glycoside, namely, lamiide (IV) were isolated from the ethyl acetate, ether and n- butanol fractions of a methanolic extract of aerial parts of Phlomis persica, respectively. Isolation and structural elucidation of compounds were accomplished by PTLC, CC, HPLC and spectroscopic methods (UV, FTIR, EIMS, 1H-NMR, 13C-NMR, DEPT, 1H- 1H COSY, HMQC and HMBC).
Keywords :
Phlomis persica , Phlomis olivieri , Flavonoid , Phenylpropanoid and Iridoid glycosids
Journal title :
Daru:Journal of Pharmaceutical Sciences
Journal title :
Daru:Journal of Pharmaceutical Sciences
