Title of article :
Synthesis, characterization and biological evaluation of dihydropyrimidine derivatives
Author/Authors :
Adhikari, Adithya Mangalore University - Department of Studies in Chemistry, India , Kalluraya, Balakrishna Mangalore University - Department of Studies in Chemistry, India , Sujith, K.V. Mangalore University - Department of Studies in Chemistry, India , Gouthamchandra Jnanasahyadri, Kuvempu University - Department of P G Studies and Research in Biotechnology and Bioinformatics, India , Mahmood, Riaz Jnanasahyadri, Kuvempu University - Department of P G Studies and Research in Biotechnology and Bioinformatics, India
Abstract :
A series of dihydropyrimidines containing quinoline were prepared under conventional heating and microwave irradiation. The structures of newly synthesized compounds were estab- lished based on analytical and spectral studies. Further these compounds were evaluated for their antioxidant, antifungal and antibacterial activities. Most of the compounds showed moderate to good activity when compared with standard.
Keywords :
Quinolinodihydropyrimi , dines , MW assisted synthesis , Three component reaction , Antioxidant activity , Antibacterial activity , Antifungal activity
Journal title :
Saudi Pharmaceutical Journal(SPJ)
Journal title :
Saudi Pharmaceutical Journal(SPJ)
