Author/Authors :
Aoyama، Yasutaka نويسنده , , Yamane، Takahisa نويسنده , , Hino، Masayuki نويسنده , , Nakamae، Hirohisa نويسنده , , Koh، Ki-Ryang نويسنده , , Takubo، Takayuki نويسنده , , Tatsumi، Noriyuki نويسنده , , Kumura، Takeo نويسنده , , Nishiki، Saori نويسنده , , Kinoshita، Yoshimitsu نويسنده , , Ohta، Kensuke نويسنده , , Kamitani، Tomio نويسنده , , Nakao، Takafumi نويسنده ,
Abstract :
We report a patient with AL amyloidosis and chemo-resistant light-chain multiple myeloma who developed a progressive malignant pericardial effusion leading to cardiac tamponade. Despite pericardiocentesis and surgical intervention, the pericardial effusion failed to resolve. The administration of oral colchicine produced symptomatic relief within 5 days, with the resolution of pericardial effusion after 14 days of treatment. As the administration of colchicine is simple and the side-effect is usually minimal, further studies are warranted to establish the feasibility of using colchicine to treat malignant pericardial effusion.
