Title of article :
Chemical Components of Marine Sponge Derived Fungus Fusarium proliferatum Collected from Pulau Tinggi, Malaysia (Komponen Kimia Kulat Fusarium proliferatum diperolehi daripada Span Marin di Perairan Pulau Tinggi, Malaysia)
Author/Authors :
MOSADEGHZAD, Z. Islamic Azad University,Sharekord Branch - Faculty of Science - Department of Chemistry, ايران , ZAKARIA, ZURIATI Universiti Kebangsaan Malaysia - Faculty of Science and Technology , School of Chemical Sciences and Food Technology, Malaysia , ASMAT, A. Universiti Kebangsaan Malaysia - Faculty of Science and Technology , School of Bio Sciences and Biotechnology, Malaysia , GIRES, U. Universiti Kebangsaan Malaysia - Faculty of Science and Technology , School of Bio Sciences and Biotechnology, Malaysia , WICKNESWARI, R. Universiti Kebangsaan Malaysia - Faculty of Science and Technology , School of Bio Sciences and Biotechnology, Malaysia , PITTAYAKHAJONWUT, P. National Science and Technology Development Agency (NSTDA) - National Centre for Genetic Engineering and Biotechnology (BIOTEC), Thailand , FARAHANI, G.H.N. Azad University,Sharekord Branch - Faculty of ScienceIslamic - Department of Chemistry, ايران
Abstract :
Marine fungus Fusarium proliferatum derived from marine sponge collected along Pulau Tinggi, Malaysia was cultivated on Potato Dextrose Broth and incubated for 7 days at 30oC. The liquid cultures were then extracted using ethyl acetate. The crude extract was investigated for its anti-microbial activity and was passed through Sephadex column and the fractions were collected. Reverse phase HPLC was used to monitor the component of crude extract. HPLC guided purification of crude extract resulted in the isolation of linoleic acid, 4-hydroxy phenethyl alcohol, 2,5-furandimethanol and adenosine. Their structures were elucidated by spectroscopic methods
