Author/Authors :
Kumar, B.S. Ashok Sri K.V. College of Pharmacy - Department of Pharmacognosy, India , Khan, Saleemulla Manipal College of Pharmaceutical Sciences - Department of Pharmacognosy, India , Saran, Gopi Setty Sri K.V.College of Pharmacy - Department of Pharmaceutics, India , Nandeesh, R. SreeSiddaganga College of Pharmacy - Department of Pharmacognosy, India , Manjunath, N.K. Sri K.V. College of Pharmacy - Department of Pharmacognosy, India
Abstract :
Nisamalaki Churna is an Ayurveda formulation used for diabetes, which consists of amalaki and haridra. In vitro antidiabetic screening of Nisamalaki Churna by α-amylase inhibition was carried out by starch iodine method, dinitrosalicylic acid method (DNSA) and effect on normal rats blood sugar level was studied. Nisamalaki Churna shows potent α-amylase inhibition IC50 89.44 μg/mL by starch iodine method and IC50100.0 μg/mL by DNS method. Nisamalaki Churna showed potent decrease in blood glucose level in normal rats.
Keywords :
α , amylase inhibition , antidiabetic screening , Nisamalaki Churna
