Author/Authors :
YADAV, SUNIL S University of Mumbai - Department of Chemistry, India , MESHRAM, GA University of Mumbai - Department of Chemistry, India , SHINDE, DATTATRAYA University of Mumbai - Department of Chemistry, India , PATIL, RC University of Mumbai - Department of Life Sciences, India , PATIL, RC Bhavan’s College - Department of Microbiology, India , MANOHAR, SONAL M University of Mumbai - Department of Life Sciences, India , UPADHYE, MADHAV V University of Mumbai - Department of Life Sciences, India
Abstract :
Syzygium cumini L. better known as Jamun belonging to the family Myrtaceae is identified to have antidiabetic, anti-inflammatory, anti-pyretic and anti-oxidant activities. Anticancer activity of S. cumini L. fruits has been demonstrated. However, anticancer activity of S. cumini seeds on various types of human cancers has not been explored much. The methanol fraction of ethanol extract from the seeds of S. cumini was found to have significant antibacterial activity. This bioactive fraction was further tested positive for its anticancer activity on various types of human cancer cell lines indicating its potency. Structural characterization of the bioactive fraction was achieved using analysis of high performance liquid chromatography, ultra violet and infra red spectrum.
Keywords :
Syzygium cumini L. , antibacterial activity , cytotoxic activity , structural characterization
