Title of article :
Effect of Functional Interleukin-10 Polymorphism on Pegylated Interferon-α Plus Ribavirin Therapy Response in Chronic Hepatitis C Virus Patients Infected With 3a Genotype in Pakistani Population
Author/Authors :
Afzal, Muhammad Sohail National University of Science and Technology - Atta-ur Rahman School of Applied Biosciences, Pakistan , Anjum, Sadia National University of Sciences and Technology - Atta ur Rahman School of Applied Biosciences, Pakistan , Zaidi, Najam Us Sahar Sadaf National University of Science and Technology - Atta ur Rahman School of Applied Biosciences, Pakistan
Abstract :
than 10 million people infected with hepatitis C Virus (HCV) with a major genotype of 3a (GT 3a). Due to high rate of resistance to standard Interferon plus Ribavirin therapy, it is highly needed to identify new marker for response prediction to therapy. Interleukin 10 (IL-10) is a key member of Cytokine, which regulates Th1/Th2 Cytokine balance, a major part of immune system against infection.
Keywords :
Hepacivirus , Interleukin , 10 , Polymorphism, Genetic , Pakistan
Journal title :
Hepatitis Monthly
Journal title :
Hepatitis Monthly
