Author/Authors :
Yılmaz, Mehmet Birhan Department of Cardiology - Faculty of Medicine - Dokuz Eylül University - İzmir - Turkey , Aksakal, Emrah Department of Cardiology - Erzurum Regional Training and Research Hospital - Erzurum - Turkey , Aksu, Uğur Department of Cardiology - Erzurum Regional Training and Research Hospital - Erzurum - Turkey , Altay, Hakan Department of Cardiology - Faculty of Medicine - Başkent University - İstanbul-Turkey , Nesligül, Yıldırım Department of Cardiology - Faculty of Medicine - Kırıkkale University - Kırıkkale - Turkey , Çelik, Ahmet Department of Cardiology - Faculty of Medicine - Mersin University - Mersin - Turkey , Akil, Mehmet Ata Department of Cardiology - Faculty of Medicine - Dicle University - Diyarbakır - Turkey , Bekar, Lütfü Department of Cardiology - Faculty of Medicine - Hitit University - Çorum - Turkey , Gökhan Vural, Mustafa Department of Cardiology - Faculty of Medicine - Sakarya University - Sakarya - Turkey , Çetin Güvenç, Rengin Department of Cardiology - Haydarpaşa Numune Training and Research Hospital - İstanbul - Turkey , Özer, Savaş Department of Cardiology - Recep Tayyip Erdoğan University Training and Research Hospital - Rize - Turkey , Ural, Dilek Department of Cardiology - Faculty of Medicine - Koç University - İstanbul - Turkey , Çavuşoğlu, Yüksel Department of Cardiology - Faculty of Medicine - Eskişehir Osmangazi University - Eskişehir - Turkey , Tokgözoğlu, Lale Department of Cardiology - Faculty of Medicine - Hacettepe University - Ankara - Turkey
Abstract :
Objective: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided.
Methods: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM.
Results: There were 1054 patients with a mean age of 63.3±13.3 years and with a median follow-up period of 16 (7–17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores ≤1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year.
Conclusion: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year.
