Author/Authors :
Norazah, M.A. Universiti Putra Malaysia - Faculty of Science - Department of Chemistry, Malaysia , Rahmani, M. Universiti Putra Malaysia - Faculty of Science - Department of Chemistry, Malaysia , Khozirah, S. Universiti Putra Malaysia - Faculty of Science - Department of Chemistry, Malaysia , Ismail, H.B.M. university of malaya - Centre for Foundation Study in Sciences, Malaysia , Sukari, M.A. Universiti Putra Malaysia - Faculty of Science - Department of Chemistry, Malaysia , Ali, A.M. Universiti Putra Malaysia - Department of Biotechnology, Malaysia , Ee, G.C.L. Universiti Putra Malaysia - Faculty of Science - Department of Chemistry, Malaysia
Abstract :
The extract of Cinnamomum microphyllum showed strong antioxidant activity when it was tested against auto-oxidation of linoleic acid, superoxide, and DPPH radical scavenging activity. Further detailed investigations of the plant constituents and bioactivity studies led to the isolation and identification of known compounds consisting of three lignans, a coumarin, an ester and β-sitosterol. The structures of the compounds were determined using detailed spectroscopic analysis. The lignans were found to possess a significant antioxidant activity when tested against the three assay systems.
Keywords :
Cinnamomum microphyllum , pinoresinol , syringaresinol , medioresinol , antioxidant