Author/Authors :
Taj, Muhammad Kamran Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Bing, Lin Lian Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Qi, Zhang Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Ling, Ji Xiu Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Taj, Imran Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Hassani, Taj Muhammad Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Samreen, Zohra Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Mangle, Aslam Kunming University of Science and Technology - Faculty of Life Science and Technology, China , Yunlin, Wei Kunming University of Science and Technology - Faculty of Life Science and Technology, China
Abstract :
The present study was an effort to look at the effect of quorum sensing molecules which are acyl-homoserine lactones and indole on production and lytic activity of T4 bacteriophage. A predator/prey system model was employed to conduct the experiment. Results obtained during the study showed that acyl-homoserine lactones (AHL), which are essential signaling molecules of quorum sensing in many Gram-negative bacteria, can increase T4 phage production and lysis against Escherichia coli BL21 (DE3) pLysS. In addition, our study showed that indole which can also act as a signaling molecule and is a common diagnostic marker for the identification of E. coli reduced the lysis activity and production of T4 bacteriophage.
Keywords :
AHL , E coli , Indole , Quorum Sensing , T4 Phage
