Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection?

Obesity is a thriving health problem, and failure to achieve weigh loss through lifestyle changes is common. Consequently, weight-loss supplements have become increasingly popular, and raspberry ketones (RK) are one such example. Animal studies suggest that RK enable weigh loss through various mechanisms, including norepinephrine-induced lipolysis (1). However, there is limited literature evaluating its effect on humans (2, 3). Despite unproven efficacy, RK are easily acquired, and may pose a potential toxicity risk, especially as dosing regimens and longterm effects are uncertain (4).