BIO-CONTROL ASSAYS OF PLANT PATHOGENIC BACTERIA WITH DIFFERENT SOLVENTS OF Datura alba NEES.

The use of plants for the treatment of various human diseases is an old practice and it still offers an enormous potential source of new anti-infective agents. Datura alba Nees (Solanaccae) is popular all over the world for its medicinal uses; hence this study was evaluated for its scientific validity. The antagonistic effect of water and organic solvents (Benzene, Chloroform and Ether) extracts of D. alba were studied against 10 pathogenic strains of bacteria. Among the 10 species, most were shown to have significant anti-bacterial activity with all of the three used extracts. Organic solvent extracts showed antibacterial effects towards Xanthomonas axonopodis, Pseudomonas syringae, Enterobacter agglomerans, Clostridium difficile, Ensifer adhaerens and water solvent extracts showed antibacterial effect towards E. agglomerans, Corynebacterium minutissium, Acidovorax temperans, Bordetella pertussis. The minimum inhibitory concentration value for bacterial pathogen ranged between 0.10 to 4.0 mg mL^-1 when tested with all the solvent extracts of D. alba. The main objective of the study was minimizing the growth of bacterial species by using different extracts/solvents of D. alba. Thus results of D. alba leaf extracts showed effective antibacterial activity with different strains of bacteria, which showed that these are confined to cure the same bacterial diseases.