Author/Authors :
Laghari, Arshad Hussain Ghulam Muhammad Mahar Medical College - Department of Biochemistry, Pakistan , Sultana, Viqar University of Karachi - Department of Biochemistry, Biotechnology and Drug Development Laboratory, Pakistan , Samoo, Akhtar Hussain Ghulam Muhammad Mahar Medical College - Department of Physiology, Pakistan , Makhija, Pirbhomal Ghulam Muhammad Mahar Medical College - Department of Medicine, Pakistan , Ara, Jehan University of Karachi - Department of Food Science and Technology, Postharvest Technology Laboratory, Pakistan , Hira University of Karachi - Department of Biochemistry, Biotechnology and Drug Development Laboratory, Pakistan
Abstract :
Objective: A Cross Sectional population based serological studies was conducted to determine the prevalence and associated risk factors for syphilis women with recurrent miscarriages. Methods: Patient’s 5ml whole blood was collected through venepuncture technique. Data were collected by all women answered a questionnaire and by investigating blood sample VDRL test and FTA-ABS test. The study was conducted in a confidential manner and numbers were used to identify the participant. Results: Total 256 women were included in the present study. Mean age of women was 29.4 years while range was 21 to 38 years (206/256). Out of the 256 samples, 05 (1.9%) were positive for active syphilis. Majority belonged to low socioeconomic group, uneducated and had previous congenital anomaly. Conclusion: Active infection with Treponema pallidum (T.P) in women belonging to low socioeconomic level were disquieting. This is probably due to illiteracy and high proportion of unsafe sexual behavior. It is also suggestive that seropositive status is often discovered in routine serological studies during pregnancy.
Keywords :
Syphilis , Treponema Pallidum infection , Recurrent miscarriages , VDRL , FTA , ABS
