Author/Authors :
kalal, Hossein Sid Atomic Energy Organization of Iran - NFCRS, Nuclear Science and Technology Research Institute, ايران , Khanchi, Ali Reza Atomic Energy Organization of Iran - NFCRS, Nuclear Science and Technology Research Institute, ايران , Konoz, Elahe islamic azad university - Department of Chemistry, ايران , Khaki, Sara islamic azad university - Department of Chemistry, ايران , Taghiof, Mohammad Atomic Energy Organization of Iran - NFCRS, Nuclear Science and Technology Research Institute, ايران , Baghdadi, Majid university of tehran - Graduate Faculty of Environment, تهران, ايران , Panahi, Homayon Ahmad islamic azad university - Department of Chemistry, ايران
Abstract :
Background: Furan has been considered to be toxic and carcinogenic. In this research, a new method was applied for the pre-concentration of furan in beverage samples followed by high-performance liquid chromatography-ultraviolet detection (HPLC-UV) determination. Results: Determination was carried out by a UV detection at 205 nm. Some of the most important parameters, including extraction solvent, extraction time, sample temperature and volume, helium flow rate and salt effect were investigated and optimized. Linear calibration curve was obtained over a concentration range of 0.005 to 0.3 μg/mL with coefficient of determination (R^2 = 0.998). Limit of detection and relative standard deviation were obtained as 0.001 μg/mL and 2.21% (n = 5), respectively. Conclusions: The proposed method was applied successfully for the determination of furan in beverage samples. Among them, cola had a detectable amount of furan.
Keywords :
Furan , Beverage samples , Pre , concentration , HPLC , UV
