Author/Authors :
Mortazavi, S.M.J. shiraz university of medical sciences - School of Allied Medical Sciences - The Center for Research in Radiological Sciences, شيراز, ايران , Mortazavi, S.M.J. shiraz university of medical sciences - School of Medicine, شيراز, ايران , Mosleh-Shirazi, M.A. shiraz university of medical sciences - Center for Research in Medical Physics and Biomedical Engineering - Radiotherapy Department, شيراز, ايران , Tavassoli, A.R. Shiraz Blood Transfusion Organization, ايران , Taheri, M. shiraz university of medical sciences - Paramedical School - Diagnostic laboratory Science and Technology Research Center, شيراز, ايران , Bagheri, Z. shiraz university of medical sciences - School of Medicine - Department of Biostatistics, شيراز, ايران , Ghalandari, R. shiraz university of medical sciences - School of Allied Medical Sciences - The Center for Research in Radiological Sciences, شيراز, ايران , Bonyadi, S. shiraz university of medical sciences - School of Allied Medical Sciences - The Center for Research in Radiological Sciences, شيراز, ايران , Shafie, M. shiraz university of medical sciences - School of Allied Medical Sciences - The Center for Research in Radiological Sciences, شيراز, ايران , Haghani, M. islamic azad university - School of Science and Research - Department of Nuclear Engineering (Radiation Medicine), ايران
Abstract :
Background: Mobile phones, use electromagnetic radiation in the microwave range. On the other hand, there is only one report on radioprotective effects of flaxseed oil. The aim of this study was to investigate the effect of irradiation of rats with microwaves and/or treatment with flaxseed oil on the induction of adaptive response to a subsequent lethal dose (LD) of gamma rays. Materials and Methods: Eighty male rats were randomly divided into 6 groups of 13-15 animals. The animals in the 1st to 5th groups received microwave exposure, microwave+flaxseed oil (dissolved in olive oil), flaxseed (continued after LD), flaxseed, and olive oil. At day 5, all animals were whole-body irradiated with a previously reported LD 50/30 of 8 Gy gamma radiation. The 6th group (controls) received the same LD 50/30, but there was not any other treatment before or after the LD. Results: No death event was observed during days 1- 9 after LD irradiation in either group. At day 10, death events started in the 4th group. Thirty days after irradiation of the animals, the survival fractions for the control group, as expected, was 53.3% while there was no death event in the 1st group (survival rate of 100% in microwave-pretreated animals). The survival fractions for the 2nd to 5th groups were 69.2%, 92.3%, 46.1%, and 61.5%, respectively. Conclusion: While these findings open new horizons in radiation protection, the radioresistance induced by microwave radiations emitted by a mobile phone may interfere with the outcome of any subsequent therapeutic application of photons or radioisotopes.
Keywords :
Microwave , adaptive response , nonionizingradiation , survival , rat
