Title of article :
Persistence, Recurrence, and Progression Rates of Superficial Bladder Tumours after Resection Using the Differentiated Technique
Author/Authors :
Langbein, S. Universitatsklinikum Mannheim - Abteilungen fur Urologie, Germany , Langbein, S. University of Amsterdam - Academisch Medisch Centrum - Department of Urology, Netherlands , Badawi, K. Universitatsklinikum Mannheim - Abteilungen fur Urologie, Germany , Haecker, A. Universitatsklinikum Mannheim - Abteilungen fur Urologie, Germany , Weiss, C. Universitatsklinikum Mannheim - Abteilungen fur Biostatistik, Germany , Hatzinger, M. Universitatsklinikum Mannheim - Abteilungen fur Urologie, Germany , Alken, P. Universitatsklinikum Mannheim - Abteilungen fur Urologie, Germany , Siegsmund, M. Freien Universitat Berlin - Akademisches Lehrkrankenhaus, Krankenhaus am Urban, Germany
Abstract :
Objective: To investigate whether the differentiated resection technique for excising superficial bladder cancer leads to higher recurrence and progression rates as compared with regular resection. Subjects and Methods: We evaluated 163 patients, 66 undergoing a differentiated and 97 a regular resection. All patients underwent a routine second resection within 6–10 weeks. Recurrence and progression rates as well as tumour persistence on second resection were analyzed. Results: Patients with differentiated resections of bladder tumours did not have higher tumour recurrence and progression rates. Also, these patients had a significantly higher percentage of tumour-free second resections (p = 0.03). Conclusion: The differentiated resection technique for excising superficial bladder cancer has no negative influence on recurrence and progression rates, but it leads to a reduced tumour persistence.
Keywords :
Bladder cancer , Differentiated resection technique , Recurrence , progression , superficial bladder cancer , Tumour persistence , Second tumour resection , Extracellular matrix
