Author/Authors :
Kaloshi, Gentian University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Roji, Arben University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Seferi, Arsen University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Cakani, Bujar University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Bushati, Teona University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Roci, Ermir University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania , Petrela, Mentor University Hospital Center “Mother Theresa” - Department of neurosurgery, Albania
Abstract :
Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, we report for the first time, a case of thoracic intramedullary metastases from a cerebral glioblastoma pre-treated with BEV. A critical and exhaustive review is provided.
Keywords :
Glioblastoma , lepto , meningeal seeding , bevacizumab.
